5-Bromo-2-thienylzinc bromide
5-Bromo-2-thienylzinc bromide
CAS: 151073-94-8
Molecular Formula: C4H2Br2SZn
5-Bromo-2-thienylzinc bromide - Names and Identifiers
5-Bromo-2-thienylzinc bromide - Physico-chemical Properties
| Molecular Formula | C4H2Br2SZn |
| Molar Mass | 307.32 |
| Density | 1.021g/mLat 25°C |
| Flash Point | 1°F |
| Exposure Limit | ACGIH: TWA 50 ppm; STEL 100 ppm (Skin)OSHA: TWA 200 ppm(590 mg/m3)NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3) |
| Sensitive | Air Sensitive |
5-Bromo-2-thienylzinc bromide - Risk and Safety
| Risk Codes | R11 - Highly Flammable R19 - May form explosive peroxides R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R40 - Limited evidence of a carcinogenic effect R37 - Irritating to the respiratory system R34 - Causes burns R14/15 - |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S33 - Take precautionary measures against static discharges. S36 - Wear suitable protective clothing. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S43 - In case of fire use ... (there follows the type of fire-fighting equipment to be used.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | UN 2056 3/PG 2 |
| WGK Germany | 1 |
| Hazard Class | 4.3 |
5-Bromo-2-thienylzinc bromide - Introduction
5-Bromo-2-thienylzinc bromide is an organometallic compound with the chemical formula C4H2Br2S2Zn. It has the following properties:
1. Appearance: White to light yellow crystalline solid.
2. solubility: soluble in common organic solvents, such as ether, dimethylformamide and dichloromethane.
3. stability: stable under dry conditions, but deliquescence in moisture.
The main use of the 5-Bromo-2-thienzinc bromide is as a reagent and catalyst in organic synthesis. It can be used for the synthesis of thiophene compounds, the activation of carboxylic acids and alkynes, etc.
The preparation of 5-Bromo-2-thienylzinc bromide typically employs the reaction of zinc bromide and 2-thiophenemethanol. First, zinc bromide is reacted with 2-thiophenol in an organic solvent with stirring under anhydrous conditions, and then the solid product is filtered and purified.
When using the 5-Bromo-2-thienylzinc bromide, note the following safety information:
1. environmental safety: it should be avoided to enter the water and soil, so as not to cause pollution to the environment.
2. storage conditions: should be stored in a dry, cool place, avoid contact with air and moisture.
3. Operation Note: Appropriate protective equipment, such as gloves and goggles, should be worn during operation to avoid contact with skin and eyes.
1. Appearance: White to light yellow crystalline solid.
2. solubility: soluble in common organic solvents, such as ether, dimethylformamide and dichloromethane.
3. stability: stable under dry conditions, but deliquescence in moisture.
The main use of the 5-Bromo-2-thienzinc bromide is as a reagent and catalyst in organic synthesis. It can be used for the synthesis of thiophene compounds, the activation of carboxylic acids and alkynes, etc.
The preparation of 5-Bromo-2-thienylzinc bromide typically employs the reaction of zinc bromide and 2-thiophenemethanol. First, zinc bromide is reacted with 2-thiophenol in an organic solvent with stirring under anhydrous conditions, and then the solid product is filtered and purified.
When using the 5-Bromo-2-thienylzinc bromide, note the following safety information:
1. environmental safety: it should be avoided to enter the water and soil, so as not to cause pollution to the environment.
2. storage conditions: should be stored in a dry, cool place, avoid contact with air and moisture.
3. Operation Note: Appropriate protective equipment, such as gloves and goggles, should be worn during operation to avoid contact with skin and eyes.
Last Update：2024-04-10 22:29:15
